Studies on the Secondary Metabolites of Endophytic Fungus Pestalotiopsis neglecta Isolated from Mangrove Plant Bruguiear gymnorrhiza

Abstract

Abstract: To investigate the secondary metabolites from endophytic fungus Pestalotiopsis neglecta which was isolated from the leaves of mangrove plant Bruguiear gymnorrhiza. A variety of chromatographic purification methods like CC,PTLC,HPLC,and Sephadex LH-20 were applied and seven compounds were isolated. Their structures were identified according to their physicochemical properties and spectral data,they are as follows:1,6,8-trihydroxy-3-(hydroxymethyl) anthraquinone (1), ergosta-4,6,8(14),22-tetraen-3-one (2), 24β-ethylcholest-4-en-3β-ol (3), 24-norcholesta-22-en-3β-ol (4),ergosta-5,7,22-trienol (5),cholesterol (6),24-methylcholest-5-en-3β,7α-diol (7).These compounds are isolated from endophytic fungus P.neglecta for the first time.

Key words: mangrove plant, Bruguiear gymnorrhiza, endophytic fungus, Pestalotiopsis neglecta

CLC Number:

R284.2

ZHONG Zhi-long1, LIN Xiu-ping1, AI Wen1, QIN Chun1,3, XIAN Jia-yun1, LIU Yong-hong1*. Studies on the Secondary Metabolites of Endophytic Fungus Pestalotiopsis neglecta Isolated from Mangrove Plant Bruguiear gymnorrhiza[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2014, 26(Suppl1): 5-8.

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Studies on the Secondary Metabolites of Endophytic Fungus Pestalotiopsis neglecta Isolated from Mangrove Plant Bruguiear gymnorrhiza

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