NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2015, Vol. 27 ›› Issue (5): 896-899.doi: 10.16333/j.1001-6880.2015.05.028

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Synthesis,Characterization and Biological Activity of Quercetin Bismuth Complexes

ZHAI Guang-yu1,2, QU Wen-tao2, MA Hai-ying1, HAN Bing1, FAN Wei-hua1*   

  1. 1 School of Nursing;2 School of Pharmacy,Zhengzhou University,Henan Zhengzhou 450052,China
  • Online:2015-05-30 Published:2015-06-05

Abstract: This paper introduced the synthesis method of quercetin-bismuth complexes.The composition of the synthesized complexes was characterized by UV-visible,IR,1H NMR spectroscopies and synchronous thermal analysis techniques. 1H NMR spectrum displayed quercetin chelated with bismuth ions at 3′-OH position.This result was confirmed by simultaneous thermal analysis.The antioxidants activity of the complexes was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH).It was shown that DPPH radical scavenging activity of free quercetin was decreased after chelation of bismuth cation.

Key words: quercetin, quercetin bismuth complexes, synthesis, characterization, free radicals

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